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Vocabulary Word

Word: sensitization

Definition: process of being made sensitive or acutely responsive to an external agent or substance; V. sensitize: make or become sensitive


Sentences Containing 'sensitization'

At that time, he proposed that the mechanism of the analgesic action of nonsteroidal antiinflammatory drugs (NSAID) was due to the prevention of pain receptor sensitization which results from an inhibition of the synthesis of prostaglandins.
Fibromyalgia, a central nervous system disorder, is described as a "central sensitization syndrome" caused by neurobiological abnormalities which act to produce physiological pain and cognitive impairments as well as neuro-psychological symptomatology.
Finally, a 2008 study noted that sugar affects opioids and dopamine in the brain, and thus might be expected to have addictive potential. It referenced "binging, withdrawal, craving and cross-sensitization", and gave each of them operational definitions in order to demonstrate behaviorally that sugar binging is a reinforcer.
His studies on the basic mechanisms involved in the development of inflammatory hyperalgesia led to the discovery that a select class of analgesics like metamizole, in contrast to the classical non-steroidal antiinflammatory drugs, are able to counteract the ongoing sensitization of the primary sensory neuron via the stimulation of the arginine/nitric oxide pathway. He recently characterized a phenomenon described as retrograde sensitization of the primary sensory neuron, which emphasizes the importance of the peripheral component of the inflammatory pain.
However, several hypotheses have been developed including "central sensitization".
Sensitization is the increase in sensitivity to a drug after prolonged use.
Sugar addiction is the term for the relationship between sugar and the various aspects of food addiction including: "bingeing, withdrawal, craving and cross-sensitization".

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